Holford Matthew, Li Naixin, Nadkarni Prakash, Zhao Hongyu
Center for Statistical Genomics and Proteomics, Yale University, New Haven, CT 06520, USA.
Bioinformatics. 2005 Apr 15;21(8):1596-602. doi: 10.1093/bioinformatics/bti153. Epub 2004 Nov 25.
Packages that support the creation of pathway diagrams are limited by their inability to be readily extended to new classes of pathway-related data.
VitaPad is a cross-platform application that enables users to create and modify biological pathway diagrams and incorporate microarray data with them. It improves on existing software in the following areas: (i) It can create diagrams dynamically through graph layout algorithms. (ii) It is open-source and uses an open XML format to store data, allowing for easy extension or integration with other tools. (iii) It features a cutting-edge user interface with intuitive controls, high-resolution graphics and fully customizable appearance.
http://bioinformatics.med.yale.edu
支持创建通路图的软件包受限于无法轻易扩展到新的通路相关数据类别。
VitaPad是一个跨平台应用程序，用户可以创建和修改生物通路图，并将微阵列数据与之整合。它在以下方面对现有软件进行了改进：（i）它可以通过图形布局算法动态创建图表。（ii）它是开源的，并使用开放的XML格式存储数据，便于与其他工具进行扩展或集成。（iii）它具有前沿的用户界面，控件直观、图形分辨率高且外观完全可定制。
http://bioinformatics.med.yale.edu
