Chandra Madhavi, Khaja Mohammad Nanne, Hussain Mohammad Mehaboob, Poduri Chetan Datta, Farees Nafeesa, Habeeb Mohammad Aejaz, Krishnan Srinivasan, Ramareddy Guntaka Venkata, Habibullah Chittoor Mohammad
Center for Liver Research and Diagnostics, Deccan College of Medical Sciences and Allied Hospitals, Zafar Gadh, Kanchan Bagh, Hyderabad, India.
Intervirology. 2004;47(6):374-6. doi: 10.1159/000080883.
The present study reports prevalence of posttransplant hepatitis B virus (HBV) and hepatitis C virus (HCV) infection in 256 patients with chronic renal failure (CRF) and with a history of either renal transplant or hemodialysis. Out of 256 patients 138 had renal transplant and 118 were on maintenance hemodialysis. Among the patients screened, 7% had HBV infection alone, 46% were infected with HCV alone, while 37.10% were found to have co-infection of both the viruses. Our findings implicate these viruses as the major cause of posttransplant hepatitis in Indian patients with CRF and indicate implementation of stringent screening procedures for these two viral infections.
本研究报告了256例慢性肾衰竭（CRF）患者中移植后乙肝病毒（HBV）和丙肝病毒（HCV）感染的患病率，这些患者有肾移植或血液透析史。256例患者中，138例接受了肾移植，118例接受维持性血液透析。在接受筛查的患者中，7%仅感染HBV，46%仅感染HCV，而37.10%的患者被发现两种病毒合并感染。我们的研究结果表明，这些病毒是印度CRF患者移植后肝炎的主要病因，并表明应对这两种病毒感染实施严格的筛查程序。
