Rolla Giovanni, Nebiolo Franco, Marsico Pietro, Guida Giuseppe, Bigo Patrizia, Riva Graziella, Zanotta Stefania
Allergologia e Immunologia Clinica, Universita di Torino e Ospedale Mauriziano Umberto I di Torino, Torino, Italy.
Int Arch Allergy Immunol. 2004 Dec;135(4):293-5. doi: 10.1159/000082322. Epub 2004 Nov 24.
The European tick, Argas reflexus, is an urban pest parasitizing urban pigeons and may cause a wide range of allergic reactions.
Specific IgE to A. reflexus, SDS-PAGE and IgE immunoblotting, performed with tick extract, were carried out in the sera of 6 patients who reported allergic reactions after tick bite.
Specific IgE to A. reflexus (RAST class ranging from 1 to 3) were detected in the sera of 6 patients who reported allergic reactions (urticaria and angioedema in 2 and anaphylaxis in the other 4 patients) after tick bite. IgE reactivity to two bands of 22 and 40 kDa were identified in the patient sera.
Allergy to A. reflexus has to be considered in allergic patients living in buildings where pigeons have their nests. The powerful sensitizing property of tick allergen is underlined by the observation that none of our patients was atopic.
欧洲蜱虫，波斯锐缘蜱，是一种寄生于城市鸽子的城市害虫，可能引发多种过敏反应。
对6例报告蜱虫叮咬后出现过敏反应的患者血清进行了针对波斯锐缘蜱的特异性IgE检测、SDS - PAGE和用蜱虫提取物进行的IgE免疫印迹分析。
在6例报告蜱虫叮咬后出现过敏反应（2例出现荨麻疹和血管性水肿，另外4例出现过敏反应）的患者血清中检测到了针对波斯锐缘蜱的特异性IgE（RAST分级为1至3级）。在患者血清中鉴定出对两条分别为22 kDa和40 kDa条带的IgE反应性。
对于居住在鸽子筑巢建筑物中的过敏患者，必须考虑对波斯锐缘蜱的过敏情况。我们的患者均非特应性个体，这一观察结果突显了蜱虫过敏原强大的致敏特性。
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