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放射性诱发的颅内脑膜瘤:6例手术病例回顾

Radiation-induced intracranial meningiomas: review of six operated cases.

作者信息

De Tommasi Antonio, Occhiogrosso Michele, De Tommasi Claudio, Cimmino Antonia, Sanguedolce Francesca, Vailati Giacomo

机构信息

Department of Neurosurgery, University of Bari, Italy.

出版信息

Neurosurg Rev. 2005 Apr;28(2):104-14. doi: 10.1007/s10143-004-0366-1. Epub 2004 Nov 25.

Abstract

It is well known that radiation can induce meningiomas. These tumors usually arise in patients with a history of low-dose radiation to the scalp for treatment of tinea capitis or high-dose radiation for a previous brain tumor. Radiation-associated meningiomas (RAMs) morphologically resemble their spontaneously arising counterparts. However, RAMs frequently present a more malignant phenotype and, as such, are diagnosed as "atypical" or "aggressive" meningiomas and occur predominantly in younger patients. This paper describes six cases of radiation-associated intracranial meningiomas in patients previously treated with low-dose radiation to the scalp for tinea capitis.

摘要

众所周知,辐射可诱发脑膜瘤。这些肿瘤通常发生在有头皮低剂量辐射治疗头癣病史或既往脑肿瘤接受高剂量辐射的患者中。辐射相关脑膜瘤(RAMs)在形态上与其自发产生的对应物相似。然而,RAMs通常表现出更恶性的表型,因此被诊断为“非典型”或“侵袭性”脑膜瘤,且主要发生在年轻患者中。本文描述了6例曾因头癣接受头皮低剂量辐射治疗的患者发生的辐射相关颅内脑膜瘤。

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