Morita Hiroki, Torii Masayoshi, Yokoyama Takako, Ebi Masahide, Takakuwa Osamu, Nakamura Atsushi, Usami Ikuji
Department of Internal Medicine and Bioregulation, Nagoya City University Graduate School of Medical Sciences.
Nihon Kokyuki Gakkai Zasshi. 2004 Oct;42(10):893-6.
A 62-year-old woman was admitted with fever and bloody sputum. A mass shadow in the left S3 and obstruction of the left B3 were seen on a chest radiograph and CT. Obstructive pneumonia was suspected, and cefotiam and imipenem/cilastatin were administered. However, this treatment did not show adequate efficacy. Bronchoscopy demonstrated a yellowish-white polypoid lesion in the left B3, but histopathological findings with HE staining yielded no definite diagnosis. Subsequently, Nocardia asteroides was detected in sputum test. A sulfamethoxazole-trimethoprim combination and minocycline were administered, and the clinical findings improved. Gram-positive microfilaments were confirmed retrospectively in the pathologic specimen, and a diagnosis of pulmonary nocardiosis was made.
一名62岁女性因发热和咯血痰入院。胸部X线片和CT显示左肺上叶前段有肿块阴影,左肺上叶前段支气管阻塞。怀疑为阻塞性肺炎,给予头孢替安和亚胺培南/西司他丁治疗。然而,该治疗效果不佳。支气管镜检查显示左肺上叶前段有黄白色息肉样病变,但苏木精-伊红染色的组织病理学检查结果未明确诊断。随后,痰检发现星形诺卡菌。给予磺胺甲恶唑-甲氧苄啶联合米诺环素治疗,临床症状改善。病理标本经回顾性检查证实有革兰氏阳性微丝,确诊为肺诺卡菌病。