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在参与宿主感染的食线虫真菌中作为毒力因子的细胞外酶。

Extracellular enzymes serving as virulence factors in nematophagous fungi involved in infection of the host.

作者信息

Huang Xiaowei, Zhao Ninghui, Zhang Keqin

机构信息

Laboratory for Conversation and Utilization of Bio-resources, Yunnan University, Kunming 650091, PR China.

出版信息

Res Microbiol. 2004 Dec;155(10):811-6. doi: 10.1016/j.resmic.2004.07.003.

Abstract

Extracellular enzymes, including serine protease, chitinase and collagenase, corresponding to the main chemical constituents of the nematode cuticle and eggshell, have been reported to be involved in the infectious process as virulence factors. This review will focus on the categories, characterization, purification, cloning and potential function of these virulence enzymes and will attempt to provide new insights into the mechanisms of fungal pathogenesis in nematodes.

摘要

据报道,包括丝氨酸蛋白酶、几丁质酶和胶原酶在内的细胞外酶与线虫角质层和卵壳的主要化学成分相对应,作为毒力因子参与感染过程。本综述将聚焦于这些毒力酶的类别、特性、纯化、克隆及潜在功能,并尝试为真菌对线虫致病机制提供新的见解。

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