Amour M-C, Mokdad A, Mayenga J-M, Belaisch-Allart J
Service de gynécologie-obstétrique, CHI Jean-Rostand, 141, Grande-Rue, 92311 Sèvres, France.
Gynecol Obstet Fertil. 2004 Nov;32(11):942-9. doi: 10.1016/j.gyobfe.2004.09.008.
To define the interest of a specific care management of pregnancies in patients exposed in utero to diethylstilbestrol, with the intention of reducing the number of spontaneous miscarriage and prematurity.
One hundred and three pregnancies in 49 patients exposed in utero to diethylstilbestrol were followed during a 4-year study, while establishing a specific care management of pregnancies in those women.
Spontaneous miscarriage rate was 18.5%, among which 16.5% before 15 weeks of pregnancy and 2% after 15 weeks of pregnancy. Premature birth rate was 41.9%, among which 10.8% of great premature birth (before 32 weeks of pregnancy), 13.5% of moderate premature birth (between 32 and 36 weeks of pregnancy), and 17.6% of minor prematurity (after 36 weeks of pregnancy). The patients' average delivery term was 36 +/-3.6 weeks.
As compared with the literature data, our miscarriage and prematurity rates are found to be lower. Our specific care management seems thus to be effective.
确定对子宫内暴露于己烯雌酚的患者进行特定妊娠护理管理的益处，旨在减少自然流产和早产的数量。
在一项为期4年的研究中，对49名子宫内暴露于己烯雌酚的患者的103次妊娠进行了随访，同时为这些女性建立了特定的妊娠护理管理。
自然流产率为18.5%，其中妊娠15周前为16.5%，妊娠15周后为2%。早产率为41.9%，其中重度早产（妊娠32周前）为10.8%，中度早产（妊娠32至36周之间）为13.5%，轻度早产（妊娠36周后）为17.6%。患者的平均分娩孕周为36±3.6周。
与文献数据相比，我们的流产率和早产率较低。因此，我们的特定护理管理似乎是有效的。
