Molecular adsorbent recycling system in treating patients with acute liver failure: a bridge to liver transplantation.
作者信息
Ding Yi-Tao, Xu Qing-Xiang, Qiu Yu-Dong, Yang Yi-Jun
机构信息
Department of Hepatobiliary Surgery, Affiliated Drum Tower Hospital of Medical College of Nanjing University; Hepatobiliary Institute of Nanjing University; Hepatobiliary Surgery Institute of Nanjing, Nanjing 210000, China.
出版信息
Hepatobiliary Pancreat Dis Int. 2004 Nov;3(4):508-10.
BACKGROUND
Acute liver failure is still a life-threatening disease although it can be treated by liver transplantation. This study was conducted to assess the molecular adsorbent recycling system (MARS), which may bridge acute liver failure patients to liver transplantation.
METHODS
Biochemical indexes and other clinical data were analyzed of 8 patients with acute liver failure, who had been treated by MARS for 34 times and subsequent Piggyback liver transplantation.
RESULTS
After treatment with MARS, the levels of transaminase and total bilirubin decreased markedly, but coagulation function remained unimproved. All patients survived and discharged from the hospital.
CONCLUSION
MARS is effective in bridging patients with acute liver failure to liver transplantation.
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