Hirst Andrew R, Smith David K
Department of Chemistry, University of York, Heslington, York YO10 5DD, United Kingdom.
Langmuir. 2004 Dec 7;20(25):10851-7. doi: 10.1021/la048178c.
The self-assembly of diaminododecane with dendritic l-lysine-based peptides to form gel-phase materials was investigated in a range of different solvents. The degree of structuring was modulated by the solvent employed, an effect which induced subtle changes in the mesoscale aggregate morphology and macroscopic behavior of the self-assembled state. In this paper a range of different solvent parameters are investigated, and it is clearly shown that macroscopic gelation can be related to a solvent polar solubility parameter for this system. The results also show a dependence on Kamlet-Taft hydrogen bonding parameters, and this clearly demonstrates the role of the solvent environment in terms of dendron--dendron intermolecular hydrogen bonding and its impact on the supramolecular chiral organization of the assembled superstructure.
研究了二氨基十二烷与基于树枝状L-赖氨酸的肽自组装形成凝胶相材料的过程，该过程在一系列不同溶剂中进行。结构程度由所使用的溶剂调节，这种效应会引起自组装态的中尺度聚集体形态和宏观行为发生细微变化。本文研究了一系列不同的溶剂参数，结果清楚地表明，宏观凝胶化与该体系的溶剂极性溶解度参数有关。结果还显示出对Kamlet-Taft氢键参数的依赖性，这清楚地证明了溶剂环境在树枝状分子间分子间氢键方面的作用及其对组装超结构的超分子手性组织的影响。
