Nofech-Mozes Y, Rachmel A, Schonfeld T, Schwarz M, Steinberg R, Ashkenazi S
Department of Paediatrics A, Schneider Children's Medical Center of Israel, Petah Tiqva, Israel.
J Paediatr Child Health. 2004 Dec;40(12):716-9. doi: 10.1111/j.1440-1754.2004.00519.x.
This study highlights the less common presentations of Hirschsprung disease (HD) and HD-associated enterocolitis (HAE) in neonates and infants. We present three infants whose diagnosis was delayed because of atypical presenting features, especially with failure to gain weight, decreased appetite, episodes of diarrhoea and vomiting and hypoalbuminaemia. The reported incidence of HAE ranges from 0 to 16.2%. To avoid complications of life-threatening HAE, primary care physicians require a high index of suspicion of the more unusual presentations of HD in neonates and infants.
本研究强调了新生儿和婴儿期先天性巨结肠（HD）及HD相关小肠结肠炎（HAE）的不常见表现。我们报告了三名婴儿，其诊断因非典型表现而延迟，尤其是体重不增、食欲减退、腹泻和呕吐发作以及低白蛋白血症。报道的HAE发病率为0%至16.2%。为避免危及生命的HAE并发症，基层医疗医生需要对新生儿和婴儿期HD的更不寻常表现保持高度怀疑。
