Ebner Roland, Schreiber Wolfgang, Zierer Christoph
Bezirksklinikum Mainkofen, Psychiatrische Klinik.
Psychiatr Prax. 2004 Nov;31 Suppl 1:S108-10. doi: 10.1055/s-2004-828448.
Comparison of buprenorphine vs. methadone to determine which medication is better for the detoxification of young opioid addicts.
93 consecutive opioid-dependent patients (ICD-10) from an in-patient detoxification unit for adolescents were investigated, of which 42 chose buprenorphine and 51 chose methadone for detoxification. Both groups did not differ with regard to different sociodemographic and addiction-specific variables such as age, gender, initiation of drug consumption and duration of opioid intake.
23.5 % of the methadone patients and 38.1 % of the buprenorphine patients finished detoxification successfully, in addition the buprenorphine patients finished detoxification 1.62 days earlier. There was no significant difference concerning these items.
Buprenorphine seems to be at least as effective as methadone for opioid withdrawal in young addicts.
比较丁丙诺啡与美沙酮，以确定哪种药物更适合年轻阿片类成瘾者的脱毒治疗。
对来自青少年住院戒毒单元的93例连续的阿片类药物依赖患者（国际疾病分类第十版）进行调查，其中42例选择丁丙诺啡进行脱毒治疗，51例选择美沙酮进行脱毒治疗。两组在不同的社会人口统计学和成瘾相关变量方面无差异，如年龄、性别、开始吸毒时间和阿片类药物摄入持续时间。
23.5%的美沙酮患者和38.1%的丁丙诺啡患者成功完成脱毒治疗，此外，丁丙诺啡组患者完成脱毒治疗的时间提前1.62天。这些项目之间无显著差异。
在年轻成瘾者的阿片类药物戒断治疗中，丁丙诺啡似乎至少与美沙酮一样有效。
