Verdú Soriano J, Rueda López J, Martínez Cuervo F, Soldevilla Agreda J
Department of Community Nursing, Preventive Medicine, Public Health, University of Alicante, Spain.
J Wound Care. 2004 Nov;13(10):419, 421-3. doi: 10.12968/jowc.2004.13.10.26685.
This exploratory, clinical study aimed to explore the effect of an activated charcoal silver dressing (intervention) with cleansing and debridement (control) in reducing the level of bacteria in chronic wounds with no clinical signs of local infection.
Patients were randomly assigned to the intervention or control group and monitored for two weeks. Samples for bacterial status and cultivation were obtained by surface smear (spatula) and percutaneous aspiration first at baseline and then after 15 days of treatment. Sixty-seven lesions were included in the intervention group and 58 in the control group.
At baseline, in the intervention group 71.6% of the wounds were contaminated, 7.5% had a high level of bacteria and 20.9% were infected. In the control group at baseline 65.5% of the wounds were contaminated, 6.9% colonised, 6.9% had a high level of bacteria and 20.7% were infected. There were no colonised wounds in the intervention group. After two weeks, combining totals of contaminated, colonised, a high level of bacteria and infection for each group, 85.1% (57/67) of the wounds in the intervention group had a positive bacterial level management (that is, a reduction in the number of bacteria in the wound) compared with 62.1% (36/58) in the control group (p=0.003).
Activated charcoal dressings that contain silver control infection and reduce healing times, eliminating bacterial barriers.
本探索性临床研究旨在探究含银活性炭敷料（干预措施）联合清创术（对照措施）对无局部感染临床症状的慢性伤口细菌水平的影响。
将患者随机分为干预组或对照组，并进行为期两周的监测。首先在基线期，然后在治疗15天后，通过表面涂片（刮铲）和经皮穿刺抽吸获取细菌状态和培养样本。干预组纳入67个伤口，对照组纳入58个伤口。
在基线期，干预组中71.6%的伤口被污染，7.5%细菌水平高，20.9%被感染。对照组在基线期，65.5%的伤口被污染，6.9%被定植，6.9%细菌水平高，20.7%被感染。干预组无定植伤口。两周后，将每组中被污染、定植、细菌水平高和感染的伤口总数合并计算，干预组85.1%（57/67）的伤口细菌水平管理呈阳性（即伤口内细菌数量减少），而对照组为62.1%（36/58）（p=0.003）。
含银活性炭敷料可控制感染并缩短愈合时间，消除细菌屏障。
