Amizuka Norio
Division of Oral Anatomy, Department of Oral Biologycal Sience, Niigata University, Graduate School of Medical and Dental Science.
Clin Calcium. 2004 Apr;14(4):589-93.
Bone is abundant in extracellular matrices, and therefore,"bone quality" appears to reflect the property of the bone matrix. The bone matrix is composed of minerals and organic materials. The volume of collagen fiber is approximately 90% of the whole organic materials of the bone matrix. Since collagen fibers could resist tension, the elasticity of the bone seems to come from the property of the collagen fibers. The mineralization of the bone matrix is achieved by the formation of hydroxyapatite crystals. The non-collagenous proteins and proteoglycans may regulate the growth of the mineralized crystal.
骨骼富含细胞外基质,因此,“骨质量”似乎反映了骨基质的特性。骨基质由矿物质和有机物质组成。胶原纤维的体积约占骨基质全部有机物质的90%。由于胶原纤维能够抵抗张力,骨骼的弹性似乎源于胶原纤维的特性。骨基质的矿化是通过羟基磷灰石晶体的形成来实现的。非胶原蛋白和蛋白聚糖可能会调节矿化晶体的生长。