Lødrup K C, Svindland A, Refvem O K, Carlsen K H
Allergologisk poliklinikk, Barneavdelingen Familie- og Barnklinikken, Ullevål sykehus, Oslo.
Tidsskr Nor Laegeforen. 1992 Feb 20;112(5):620-2.
During four winter months 1989-90, two children died suddenly from asthma, and one suffered a life threatening attack. A 20 months old boy with moderately severe asthma, just recovered from an adenovirus infection, was symptom free at a routine consultation less than 12 hours before death. He died suddenly after a spell of coughing. A six year old girl with severe but well controlled asthma received unknown quantities of inhaled nebulized salbutamol during a three day exacerbation. She died at home due to respiratory arrest. A 16 year old boy who attended the clinic sporadically had a severe uncontrolled attack of asthma. He inhaled at least 400 doses of salbutamol via a metered dose inhaler during the two days prior to a sudden respiratory arrest. He was successfully resuscitated. This paper addresses possible mechanisms underlying different types of severe attacks of asthma.
在1989 - 1990年的四个冬季月份里，有两名儿童因哮喘突然死亡，一名儿童遭受了危及生命的哮喘发作。一名20个月大的患有中度严重哮喘的男孩，刚从腺病毒感染中康复，在死亡前不到12小时的常规会诊时无症状。他在一阵咳嗽后突然死亡。一名6岁患有严重但病情得到良好控制的哮喘女孩，在三天的病情加重期间吸入了数量不明的雾化沙丁胺醇。她在家中因呼吸骤停死亡。一名16岁的男孩偶尔到诊所就诊，发生了一次严重的、未得到控制的哮喘发作。在突然呼吸骤停前两天，他通过定量吸入器吸入了至少400剂沙丁胺醇。他成功复苏。本文探讨了不同类型严重哮喘发作潜在的可能机制。
