一种来自宽叶伞莎草的新型细胞毒性萘醌。

A new cytotoxic naphthoquinone from Paepalanthus latipes.

作者信息

Kitagawa Rodrigo Rezende, Raddi Maria Stella Gonçalves, Santos Lourdes Campaner Dos, Vilegas Wagner

机构信息

Instituto de Química de Araraquara, Universidade Estadual Paulista Júlio de Mesquita Filho, Rua Prof. Francisco Degni, Araraquara, SP, Brazil.

出版信息

Chem Pharm Bull (Tokyo). 2004 Dec;52(12):1487-8. doi: 10.1248/cpb.52.1487.

DOI:10.1248/cpb.52.1487

PMID:15577252

Abstract

Quinones constitute an important class of naturally occurring compounds. They are found in plants, fungi and bacteria. Large number of quinones has been associated with antitumor, antibacterial, antimalarial and antifungal activities. In this work we describe the isolation, structure determination and the cytotoxic index of a new 1,4-naphthoquinone isolated from the capitula of Paepalanthus latipes.

摘要

醌类是一类重要的天然存在的化合物。它们存在于植物、真菌和细菌中。大量的醌类化合物具有抗肿瘤、抗菌、抗疟疾和抗真菌活性。在这项工作中，我们描述了从宽叶拟花蔺头状花序中分离出的一种新的1,4-萘醌的分离、结构测定和细胞毒性指数。