Werchniak Andrew E, Schwarzenberger Kathryn
Department of Dermatology, Dartmouth Medical School and Dartmouth-Hitchcock Medical Center, Hanover, New Hampshire, USA.
J Am Acad Dermatol. 2004 Nov;51(5 Suppl):S159-60. doi: 10.1016/j.jaad.2004.04.019.
The relationship between herpes simplex virus (HSV) and erythema multiforme (EM) has been well described. Many authors contend that EM (excluding Stevens-Johnson syndrome and toxic epidermal necrolysis) occurs almost exclusively as a response to HSV infection. During the past year, however, we have observed several cases of EM complicating severe Rhus allergic contact dermatitis. Although this association has been previously documented, the paucity of cases in the literature, along with our experience, suggests that this is an underreported phenomenon. We describe 4 of our cases.
单纯疱疹病毒（HSV）与多形红斑（EM）之间的关系已有详尽描述。许多作者认为，EM（不包括史蒂文斯－约翰逊综合征和中毒性表皮坏死松解症）几乎仅作为对HSV感染的反应而发生。然而，在过去一年中，我们观察到几例多形红斑并发严重漆树过敏性接触性皮炎的病例。尽管这种关联此前已有文献记载，但文献中病例稀少，加上我们的经验表明，这是一种报道不足的现象。我们描述了我们的4例病例。
