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在美国,内镜检查是否有能力为未接受筛查的人群提供结直肠癌筛查?

Is there endoscopic capacity to provide colorectal cancer screening to the unscreened population in the United States?

作者信息

Seeff Laura C, Manninen Diane L, Dong Fred B, Chattopadhyay Sajal K, Nadel Marion R, Tangka Florence K L, Molinari Noelle-Angelique M

机构信息

Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia 30341-3717, USA.

出版信息

Gastroenterology. 2004 Dec;127(6):1661-9. doi: 10.1053/j.gastro.2004.09.052.

Abstract

BACKGROUND & AIMS: Screening rates for colorectal cancer remain low compared with screening rates for other cancers. The size of the unscreened population and the capacity to provide widespread screening are unknown. We estimated the number of average-risk persons aged 50 years or older not screened for colorectal cancer, the number of procedures required for this population, and the endoscopic capacity to satisfy this unmet need.

METHODS

Using data from the US Census Bureau and the Centers for Disease Control and Prevention's National Health Interview Survey, we designed a forecasting model to estimate the number of persons in the United States currently not screened for colorectal cancer and the number of examinations needed to screen these persons. Test need was compared with available capacity, based on results from the national Survey of Endoscopic Capacity, assuming different proportions of available capacity were used for colorectal cancer screening.

RESULTS

Approximately 41.8 million average-risk people aged 50 years or older have not been screened for colorectal cancer according to national guidelines. Sufficient capacity exists to screen the unscreened population within 1 year using fecal occult blood testing followed by diagnostic colonoscopy for positive tests. Depending on the proportion of available capacity used for colorectal cancer screening, it could take up to 10 years to screen the unscreened population using flexible sigmoidoscopy or colonoscopy.

CONCLUSIONS

The capacity exists for widespread screening with fecal occult blood testing. The capacity for screening with flexible sigmoidoscopy or colonoscopy depends on the proportion of available capacity used for colorectal cancer screening.

摘要

背景与目的

与其他癌症的筛查率相比,结直肠癌的筛查率仍然较低。未接受筛查人群的规模以及提供广泛筛查的能力尚不清楚。我们估计了年龄在50岁及以上未接受结直肠癌筛查的平均风险人群数量、该人群所需的检查数量以及满足这一未满足需求的内镜检查能力。

方法

利用美国人口普查局和疾病控制与预防中心的国家健康访谈调查数据,我们设计了一个预测模型,以估计美国目前未接受结直肠癌筛查的人数以及筛查这些人所需的检查数量。根据全国内镜检查能力调查结果,假设将不同比例的可用能力用于结直肠癌筛查,将检测需求与可用能力进行比较。

结果

根据国家指南,约有4180万年龄在50岁及以上的平均风险人群尚未接受结直肠癌筛查。存在足够的能力在1年内对未筛查人群进行筛查,方法是先进行粪便潜血检测,然后对检测呈阳性者进行诊断性结肠镜检查。根据用于结直肠癌筛查的可用能力比例,使用乙状结肠镜检查或结肠镜检查对未筛查人群进行筛查可能需要长达10年的时间。

结论

存在进行粪便潜血检测广泛筛查的能力。使用乙状结肠镜检查或结肠镜检查进行筛查的能力取决于用于结直肠癌筛查的可用能力比例。

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