Bakht F R, Gentry L O
Department of Family Medicine, Baylor College of Medicine, Houston, Texas.
Am Fam Physician. 1992 Apr;45(4):1683-90.
Toxoplasmosis is usually asymptomatic in pregnant women but poses a risk of severe effects on the fetus. One to eight of every 1,000 pregnant women become infected, and the infection is transmitted to the fetus in approximately 40 percent of these cases. The risk of transmission rises with increasing gestational age at the time of initial infection. Congenital infection with toxoplasmosis may lead to serious sequelae, such as blindness, mental retardation, neurologic deficits and deafness. Prevention of morbidity from toxoplasmosis depends on prevention of the infection in pregnant women, plus early recognition and aggressive treatment of maternal infections.
弓形虫病在孕妇中通常无症状，但对胎儿有造成严重影响的风险。每1000名孕妇中有1至8人会受到感染，其中约40%的病例会将感染传播给胎儿。初次感染时，传播风险会随着孕周增加而上升。先天性弓形虫感染可能导致严重的后遗症，如失明、智力迟钝、神经功能缺损和失聪。预防弓形虫病发病取决于预防孕妇感染，以及对母体感染的早期识别和积极治疗。
