Hengst P
Zentralbl Gynakol. 1982;104(15):949-56.
Primary toxoplasma gondii infection in pregnancy (6.7 per thousand pregnancies) is considered to be a potential danger to foetal development (congenital infections in 5.3 per thousand). This conclusion had been drawn from a prospective study into 1,697 pregnant women. It is a primary infection which can be detected only by means of specific diagnostic methods. - Pyrimethamine-sulphonamide treatment ,ist be considered as the optional for pregnant women, even by all accounts of side-effects. The risk of foetal infection has been reduced from 64 to 14 per cent by use of such treatment on cases of primary infection. - The results so far obtained from examination of congenitally infected children, aged between nine and ten years, are likely to justify the recommendation of general toxoplasma gondii testing and specific therapy for all cases of primary infection during pregnancy.
孕期原发性弓形虫感染(每千次妊娠中有6.7例)被认为对胎儿发育存在潜在危险(每千次中有5.3例先天性感染)。这一结论来自对1697名孕妇的前瞻性研究。这是一种原发性感染,只能通过特定的诊断方法检测出来。—— 即使考虑到所有副作用,乙胺嘧啶 - 磺胺治疗仍被视为孕妇的首选治疗方法。通过对原发性感染病例使用这种治疗,胎儿感染风险已从64%降至14%。—— 到目前为止,对9至10岁先天性感染儿童的检查结果可能证明,对孕期所有原发性感染病例进行常规弓形虫检测和特异性治疗的建议是合理的。