Woodings S
Medical Engineering and Physics, Royal Perth Hospital, Perth, Australia.
Australas Phys Eng Sci Med. 2004 Sep;27(3):118-28. doi: 10.1007/BF03178671.
Iodine-131 patients pose a radiation risk to their family members, carers and colleagues. Doses from thyrotoxicosis and thyroid cancer patients undergoing standard treatments have been well characterised in the literature. However the resulting precautions cannot be easily adapted to circumstances where the patient has an unusual affliction, or an atypical family or occupational environment. In this study, a model for calculating dose from an I-131 patient is derived from first principles. The model is combined with existing results from the literature to determine a distance weighting factor between patients and family members. This technique reduces the uncertainty in the dose calculations by removing the need to guess the unknown patterns of close contact, a problem common to all previous dose calculation techniques. Data is presented for four unusual I-131 treatments; a child thyroid cancer patient, two thyroid cancer dialysis patients and a phaeochromocytoma patient. The model is used to calculate appropriate periods of restricted contact for these patients. The recommendations provide a useful guide for future unusual I-131 treatments.
碘 - 131患者会对其家庭成员、护理人员和同事构成辐射风险。文献中已对接受标准治疗的甲状腺毒症和甲状腺癌患者的辐射剂量进行了充分描述。然而,对于患者患有特殊疾病或处于非典型家庭或职业环境的情况,现有的预防措施难以适用。在本研究中,从第一原理推导出了一种计算碘 - 131患者辐射剂量的模型。该模型与文献中的现有结果相结合,以确定患者与家庭成员之间的距离加权因子。通过消除猜测密切接触未知模式的需求,这项技术降低了剂量计算的不确定性,而这是以往所有剂量计算技术都存在的问题。文中给出了四种特殊碘 - 131治疗的数据;一名儿童甲状腺癌患者、两名甲状腺癌透析患者和一名嗜铬细胞瘤患者。该模型用于计算这些患者的适当限制接触期。这些建议为未来特殊的碘 - 131治疗提供了有用的指导。