Sládková H, Jansa P, Susa Z, Aschermann M
II. interní klinika 1. lékarské fakulty UK a VFN, Praha.
Vnitr Lek. 2004 Sep;50(9):685-8.
Pulmonary hypertension is present when the mean pulmonary pressure is increased above 25 mm Hg in a rest or above 30 mm Hg during exercise. It is possible to divide it from different point of view. Well known is pathophysiologic classification and Venice classification suggested by WHO symposium 2003. The rise of arterial pulmonary pressure is caused by three essential abnormalities, these are elevated pulmonary vascular resistance, blood flow and pulmonary artery wedge pressure. Vasoconstriction, remodeling of vessels and in situ trombosis are pathogenetic mechanism which contribute to rise of pulmonary hypertension.
当静息时平均肺动脉压升高超过25 mmHg或运动时超过30 mmHg时，即存在肺动脉高压。从不同角度对其进行分类是可行的。2003年世界卫生组织研讨会提出的病理生理分类和威尼斯分类是众所周知的。肺动脉压升高由三个基本异常引起，即肺血管阻力升高、血流量增加和肺动脉楔压升高。血管收缩、血管重塑和原位血栓形成是导致肺动脉高压升高的发病机制。
