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视网膜母细胞瘤眼球摘除术后多孔聚乙烯植入物暴露的处理

Management of porous polyethylene implant exposure in patients with retinoblastoma following enucleation.

作者信息

Kim Jong-Hyun, Khwarg Sang-In, Choung Ho Kyung, Yu Young Suk

机构信息

Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.

出版信息

Ophthalmic Surg Lasers Imaging. 2004 Nov-Dec;35(6):446-52.

Abstract

BACKGROUND AND OBJECTIVE

To report the features and the management of porous polyethylene implant exposure in patients with retinoblastoma following enucleation.

PATIENTS AND METHODS

The medical records of 33 patients (33 sockets) following enucleation and porous polyethylene implantation for retinoblastoma were reviewed.

RESULTS

The mean age at enucleation was 24 months (range, 2 to 85 months). The exposure rate was 33% (11 cases), and the mean time from enucleation to exposure was 15 months (range, 7 to 29 months). One case was resolved only by supportive management, and the remaining 10 were successfully treated with a scleral patch graft and maintained well during a mean follow-up of 15 months after surgical repair. There was no statistical evidence that age, gender, implant size, or chemotherapy had an effect on implant exposure.

CONCLUSIONS

Porous polyethylene implant exposure does not seem to be resolved by conservative management. We recommend early surgical management, such as scleral patch graft, as opposed to supportive management.

摘要

背景与目的

报告视网膜母细胞瘤眼球摘除术后多孔聚乙烯植入物暴露的特征及处理方法。

患者与方法

回顾性分析33例视网膜母细胞瘤患者(33个眼窝)眼球摘除并植入多孔聚乙烯后的病历资料。

结果

眼球摘除时的平均年龄为24个月(范围2至85个月)。暴露率为33%(11例),从眼球摘除到暴露的平均时间为15个月(范围7至29个月)。1例仅通过支持治疗得到解决,其余10例通过巩膜补片移植成功治疗,术后平均随访15个月期间情况良好。没有统计学证据表明年龄、性别、植入物大小或化疗对植入物暴露有影响。

结论

多孔聚乙烯植入物暴露似乎无法通过保守治疗解决。我们建议早期进行手术治疗,如巩膜补片移植,而不是支持治疗。

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