兔多孔聚乙烯眶植入物上自由移植眶脂肪的存活情况。
The survival of freely grafted orbital fat on porous polyethylene orbital implants in the rabbit.
作者信息
Kim Nam Ju, Choung Ho Kyung, Khwarg Sang In
机构信息
Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.
出版信息
Korean J Ophthalmol. 2006 Sep;20(3):143-6. doi: 10.3341/kjo.2006.20.3.143.
PURPOSE
To investigate the long term survival of orbital fat grafted on a Medpor implant as a method of preventing porous polyethylene orbital implant (Medpor) exposure in anophthalmic sockets.
METHODS
In one orbit in each of 8 rabbits, a small amount of retrobulbar orbital fat was grafted between the anterior surface of the Medpor implant and overlying conjunctiva, during the enucleation and Medpor implantation procedure. Two rabbits were sacrificed at 2, 4, 8 and 12 weeks postoperatively and grafted orbital fats were examined by light microscopy.
RESULTS
Grafted orbital fat was well-maintained at 2 and 4 weeks, postoperatively. However, fat amounts were significantly reduced at 8 weeks, and viable fat was barely visible at 12 weeks.
CONCLUSIONS
In rabbits, orbital fat grafted on Medpor implants was gradually resorbed, and the fat-occupied volume was not maintained.
目的
研究将眼眶脂肪移植到Medpor植入物上作为预防无眼球眼眶中多孔聚乙烯眼眶植入物（Medpor）暴露的一种方法的长期存活率。
方法
在8只兔子的每只兔子的一个眼眶中，在眼球摘除和Medpor植入过程中，在Medpor植入物的前表面和覆盖的结膜之间移植少量球后眼眶脂肪。术后2、4、8和12周分别处死2只兔子，通过光学显微镜检查移植的眼眶脂肪。
结果
术后2周和4周移植的眼眶脂肪保存良好。然而，8周时脂肪量显著减少，12周时几乎看不到存活的脂肪。
结论
在兔子中，移植到Medpor植入物上的眼眶脂肪逐渐被吸收，脂肪占据的体积未得到维持。
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