异丁香烯A，一种倍半萜生物合成过程中推测的中间体。

Isogermacrene A, a proposed intermediate in sesquiterpene biosynthesis.

作者信息

Hackl Thomas, König Wilfried A, Muhle Hermann

机构信息

Institut für Organische Chemie, Universität Hamburg, Martin-Luther-King-Platz 6, D-20146 Hamburg, Germany.

出版信息

Phytochemistry. 2004 Aug;65(15):2261-75. doi: 10.1016/j.phytochem.2004.05.024.

DOI:10.1016/j.phytochem.2004.05.024

PMID:15587711

Abstract

In the essential oil of the liverwort Saccogyna viticulosa, collected on the island of Madeira, the new sesquiterpene hydrocarbons isogermacrene A (5) and its Cope rearrangement product iso-beta-elemene (6) were identified. 5 is proposed to act as the biogenetic precursor of several new sesquiterpenes identified in the volatiles of S. viticulosa. These include iso-alpha-humulene, alpha-gorgonene, gorgona-1,4(15), 11-triene and gorgon- 11-en-4-ol. In addition, the Cope product of zierene, isozierene, allo-aromadendra-4(15),10(14)-diene, aromadendra-4(15),10(14)-dien-1-ol and a prenylguaiane diterpene alcohol, named viticulol, were identified as new natural products.

摘要

在马德拉岛采集的叶苔类植物葡萄叶苔（Saccogyna viticulosa）的精油中，鉴定出了新的倍半萜烃类化合物异丁香烯A（5）及其科普重排产物异β-榄香烯（6）。5被认为是葡萄叶苔挥发物中鉴定出的几种新倍半萜的生物合成前体。这些包括异α-葎草烯、α-戈尔戈烯、戈尔戈纳-1,4(15),11-三烯和戈尔戈纳-11-烯-4-醇。此外，还鉴定出了蛇床烯的科普产物、异蛇床烯、别-香树烯-4(15),10(14)-二烯、香树烯-4(15),10(14)-二烯-1-醇以及一种异戊烯基愈创木烷二萜醇（命名为葡萄叶醇）作为新的天然产物。