巨噬细胞A类清道夫受体marco的结构与功能
The structure and function of marco, a macrophage class a scavenger receptor.
作者信息
Arredouani M S, Kobzik L
机构信息
Physiology Program, Harvard School of Public Health, Boston, MA 02115, USA.
出版信息
Cell Mol Biol (Noisy-le-grand). 2004;50 Online Pub:OL657-65.
PMID:15588554
Abstract
The class A scavenger receptors are important in many aspects of macrophage biology. The receptor MARCO is a relatively recently described member of this class. The biological role of MARCO is under active investigation, and shows interesting similarities and contrasts to that of the class prototype, SR-A-I/II. This review surveys current knowledge and unanswered questions regarding the structure and function of the MARCO receptor.
摘要
A类清道夫受体在巨噬细胞生物学的许多方面都很重要。受体MARCO是该类中相对较新描述的成员。MARCO的生物学作用正在积极研究中，与该类原型SR-A-I/II相比，显示出有趣的异同点。本综述概述了关于MARCO受体结构和功能的现有知识及未解决的问题。
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