Burridge L E, Haya K, Waddy S L
Marine Environmental Sciences Division, Fisheries and Oceans Canada, St. Andrews Biological Station, 531 Brandy Cove Rd., St. Andrews, NB, Canada E5B 2L9.
Ecotoxicol Environ Saf. 2005 Mar;60(3):277-81. doi: 10.1016/j.ecoenv.2004.06.004.
The organophosphate pesticide azamethiphos is the active ingredient in Salmosan, a product formerly registered in Canada for the treatment of cultured Atlantic salmon against infestations of the ectoparasite Lepeophtheirus salmonis. The 48-h LC50 of azamethiphos to female American lobsters was determined bimonthly for 2 years to determine whether the sensitivity of lobsters to azamethiphos varied with time of year, molt stage, or reproductive stage. The LC50's ranged from 0.61 to 3.24 microg/L. The lobsters were most sensitive to azamethiphos during the spawning and molting seasons which occur in the summer and early fall when seawater temperatures are highest. Testing of compounds on this species for regulatory purposes should take into account that there may be variations in sensitivity during the molt and reproductive cycles.
有机磷农药唑磷是Salmosan中的活性成分，该产品曾在加拿大注册用于养殖大西洋鲑鱼，以防治体外寄生虫鲑鱼虱的侵扰。为了确定龙虾对唑磷的敏感性是否随年份、蜕皮阶段或繁殖阶段而变化，对雌性美国龙虾每两个月测定一次唑磷的48小时半数致死浓度（LC50），为期两年。LC50范围为0.61至3.24微克/升。龙虾在夏季和初秋海水温度最高时出现的产卵和蜕皮季节对唑磷最为敏感。出于监管目的对该物种进行化合物测试时，应考虑到在蜕皮和繁殖周期中敏感性可能存在差异。
