亚硝酸异丁酯滥用后短暂性视力丧失。

Transient visual loss after amyl Isobutyl nitrite abuse.

作者信息

Pece Alfredo, Patelli Fabio, Milani Paolo, Pierro Luisa

机构信息

Clinica Oculistica, Ospedale di Melegnano, Vizzolo Predabissi, Italy.

出版信息

Semin Ophthalmol. 2004 Sep-Dec;19(3-4):105-6. doi: 10.1080/08820530490882292.

DOI:10.1080/08820530490882292

PMID:15590547

Abstract

PURPOSE

To report retinal alterations after Isobutyl nitrite (popper) inhalation.

METHODS

Case Report.

RESULTS

A 30-year-old man presented a sudden visual decrease following the use of Isobutyl nitrite (popper) while he was at a discotheque. His visual acuity (VA) was 20/50 in the right eye (RE) and 20/63 in the left eye (LE). Ophthalmoscopy revealed symmetric alteration of the foveal reflex with a small yellowish-white spot in the foveal area, much more evident in the RE. Fluorescein angiography and OCT were normal. Visual field showed a mild reduction of central differential light sensitivity. A progressive recovery was noted and at one month's follow-up VA was 20/25 in OU with very faint yellowish-white spots.

CONCLUSIONS

The inhalation of drugs as "popper" may cause a visual loss by unclear mechanisms.

摘要

目的

报告吸入亚硝酸异丁酯（Poppers）后视网膜的改变。

方法

病例报告。

结果

一名30岁男性在迪斯科舞厅使用亚硝酸异丁酯（Poppers）后突然视力下降。右眼视力（VA）为20/50，左眼为20/63。检眼镜检查发现黄斑反射对称改变，黄斑区有一个小的黄白色斑点，右眼更明显。荧光素血管造影和光学相干断层扫描（OCT）均正常。视野检查显示中心差分光敏感度轻度降低。观察到视力逐渐恢复，随访1个月时双眼视力为20/25，黄白色斑点非常淡。