Dolphin W F, Mountain D C
Department of Biomedical Engineering, Boston University, Massachusetts 02215.
Hear Res. 1992 Feb;58(1):70-8. doi: 10.1016/0378-5955(92)90010-k.
Scalp potentials which follow the low frequency envelope of a sinusoidally amplitude modulated stimulus waveform were evoked and recorded in anesthetized gerbils. This envelope following response (EFR) is presumably due to the synchronized discharge of populations of neurons in the auditory pathway. The magnitude of the EFR increased and the latency decreased in a near monotonic fashion with increased stimulus intensity and modulation depth. The modulation rate transfer function (MRTF) was determined for modulation frequencies between 10 and 920 Hz imposed on carrier frequencies ranging from 1 to 7 kHz. The MRTF was low pass in character having a corner frequency of 100-120 Hz. Measurements of the group delay, determined from the phase of the response relative to the stimulus phase, indicate that the response is generated in at least three distinct regions within the auditory pathway.
在麻醉的沙鼠中诱发并记录了跟随正弦幅度调制刺激波形低频包络的头皮电位。这种包络跟随反应(EFR)可能是由于听觉通路中神经元群体的同步放电所致。随着刺激强度和调制深度的增加,EFR的幅度几乎以单调方式增加,潜伏期缩短。确定了施加在1至7 kHz载波频率上的10至920 Hz调制频率的调制率传递函数(MRTF)。MRTF具有低通特性,截止频率为100 - 120 Hz。根据反应相对于刺激相位的相位确定的群延迟测量表明,该反应是在听觉通路内至少三个不同区域产生的。