Alawi Faizan, Siddiqui Asma
Department of Pathology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104-6002, USA.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005 Jan;99(1):79-84. doi: 10.1016/j.tripleo.2004.05.007.
Fordyce granules are found in the oral mucosa of up to 80% of adults. However, primary malignant sebaceous tumors of the oral mucosa are exceedingly rare. To our knowledge, only 5 examples of intraoral sebaceous carcinoma have been reported in the literature. This report describes a primary sebaceous carcinoma of the labial mucosa that arose in an area containing numerous Fordyce granules. A brief review of the clinical and histopathologic features of sebaceous carcinoma is also presented.
福代斯颗粒见于高达80%的成年人的口腔黏膜中。然而,口腔黏膜原发性恶性皮脂腺肿瘤极为罕见。据我们所知,文献中仅报道过5例口腔内皮脂腺癌。本报告描述了一例发生于含有大量福代斯颗粒区域的唇黏膜原发性皮脂腺癌。本文还简要回顾了皮脂腺癌的临床和组织病理学特征。