Xu Qunyuan, Grant Gunnar
Department of Neuroscience, Karolinska Institutet, 171 77, Stockholm, Sweden.
Exp Brain Res. 2005 Apr;162(2):250-6. doi: 10.1007/s00221-004-2132-6. Epub 2004 Dec 15.
The course of retrogradely labeled spinocerebellar fibers in the ventral and lateral funiculi of the spinal cord was studied following injections of wheat germ agglutinin-conjugated horseradish peroxidase into the posterior spinocerebellar termination area in the cat. Fibers labeled from unilateral injections into the paramedian lobule were found on the same side in the dorsal part of the lateral funiculus (DLF), corresponding to the dorsal spinocerebellar tract (DSCT), but contralaterally in the ventral part of the lateral funiculus (VLF) and in the ventral funiculus (VF), corresponding to the ventral spinocerebellar tract (VSCT). Following injections into the posterior vermis, labeled fibers were less numerous. Most of them were found in the DSCT and only very few in the VSCT. Previously identified cells of origin of these spinocerebellar tracts were labeled in these experiments and counted. They correlated well with the extents and the locations of the injections that had been made into the two termination sites. These results represent novel detailed information on the location of axons projecting to the two main posterior spinocerebellar termination sites in the spinal white matter in the cat.
将麦胚凝集素结合辣根过氧化物酶注射到猫的后脊髓小脑终止区域后，对脊髓腹侧和外侧索中逆行标记的脊髓小脑纤维的走行进行了研究。从单侧注射到旁正中小叶的纤维在同侧外侧索背侧部分（DLF）被发现，对应于背侧脊髓小脑束（DSCT），但在对侧外侧索腹侧部分（VLF）和腹侧索（VF）被发现，对应于腹侧脊髓小脑束（VSCT）。向后蚓部注射后，标记纤维数量较少。它们大多在DSCT中被发现，而在VSCT中只有极少数。在这些实验中对这些脊髓小脑束先前确定的起源细胞进行了标记和计数。它们与注射到两个终止部位的范围和位置密切相关。这些结果代表了关于猫脊髓白质中投射到两个主要后脊髓小脑终止部位的轴突位置的新的详细信息。
