Course of spinocerebellar axons in the ventral and lateral funiculi of the spinal cord with projections to the anterior lobe: an experimental anatomical study in the cat with retrograde tracing techniques.

The fiber course of the spinocerebellar tracts in the ventral and lateral funiculi of the cat spinal cord were studied by a new approach, making cordotomies at different spinal levels or lesions of the restiform body followed by injections of HRP or WGA-HRP into the anterior cerebellar lobe. The retrogradely labeled axons showed characteristic distribution patterns related to the level and extent of the lesions. The results show the following. 1) The dorsal spinocerebellar tract (DSCT) originating ipsilaterally from the thoracic and upper lumbar segments ascends in the dorsolateral fasciculus. It undergoes a dorsal shift during its rostral course. The tract is topically arranged and passes through the restiform body. 2) The ventral spinocerebellar tract (VSCT) arising contralaterally from lower thoracic, lumbar, and more caudal segments passes via the ventral funiculus and ascends in the ventrolateral fasciculus. This tract is also topically arranged. It makes a lateral and then a dorsal shift during its ascending course. The main portion of the VSCT enters the cerebellum via the superior cerebellar peduncle. A minor portion originating from the sacrococcygeal region enters via the restiform body. 3) The spinocerebellar fibers originating ipsilaterally from the cervical enlargement ascend in the lateralmost part of the lateral funiculus in the area between the dorsolateral and ventrolateral fasciculi. These fibers form two groups, one passing through the restiform body, the other through the superior cerebellar peduncle. 4) The spinocerebellar fibers originating contralaterally from the central cervical nucleus pass through the ventral funiculus and ascend in the lateralmost part of the lateral funiculus, mainly in the ventrolateral fasciculus. Most of the fibers seem to pass through the superior cerebellar peduncle.