Lameire Norbert, Van Biesen Wim
Department of Internal Medicine, Renal Division, Ghent University Hospital, Ghent, Belgium.
J Nephrol. 2004 Nov-Dec;17 Suppl 8:S58-66.
This paper reviews the evaluation of volume status in peritoneal dialysis (PD) and the epidemiology of protocols assessing the hydration status in PD patients, in addition the factor contributing to fluid overload in PD patients, among them the peritoneal transport characteristics, being the most important, are discussed. Long term structural and functional alteration in the membrane occur which may affect the peritoneal ultrafiltration capacity. Finally, the most important therapeutic options to treat hypervolemia in PD patients are discussed, including dietary salt restriction, the prescription of loop diuretics and the application of low sodium dialysate and polyglucose solutions.
本文综述了腹膜透析(PD)中容量状态的评估以及评估PD患者水化状态的方案的流行病学,此外,还讨论了导致PD患者液体超负荷的因素,其中腹膜转运特性是最重要的因素。腹膜会发生长期的结构和功能改变,这可能会影响腹膜超滤能力。最后,讨论了治疗PD患者高血容量的最重要的治疗选择,包括饮食限盐、袢利尿剂的处方以及低钠透析液和聚葡萄糖溶液的应用。