醋酸杆菌属和沙雷氏菌属菌株将杂环醛和芳香醛氧化为相应的羧酸。
Oxidation of heterocyclic and aromatic aldehydes to the corresponding carboxylic acids by Acetobacter and Serratia strains.
作者信息
Mitsukura Koichi, Sato Yukihide, Yoshida Toyokazu, Nagasawa Toru
机构信息
Department of Biomolecular Science, Gifu University, 1-1 Yanagido, Gifu, 501-1193, Japan.
出版信息
Biotechnol Lett. 2004 Nov;26(21):1643-8. doi: 10.1007/s10529-004-3513-4.
Conversion of heterocyclic and aromatic aldehydes to the corresponding carboxylic acids was carried out using Acetobacter rancens IFO3297, A. pasteurianus IFO13753 and Serratia liquefaciens LF14. IFO3297 produced 110 g 2-furoic acid l(-1) from furfural with a 95% molar yield. 5-Hydroxymethyl-2-furancarboxylic acid was produced from the corresponding aldehyde by using whole cells LF14. IFO13753 and LF14 both converted isophthalaldehyde, 2,5-furandicarbaldehyde, 2,5-thiophenedicarbaldehyde and 2,2' biphenyldicarbaldehyde to the corresponding formylcarboxylic acid with 86-91% molar yields.
利用 rancens 醋杆菌 IFO3297、巴斯德醋杆菌 IFO13753 和液化沙雷氏菌 LF14 将杂环醛和芳香醛转化为相应的羧酸。IFO3297 从糠醛生产出 110 g/L 的 2-呋喃甲酸，摩尔产率为 95%。通过使用全细胞 LF14 从相应的醛生产出 5-羟甲基-2-呋喃甲酸。IFO13753 和 LF14 都将间苯二甲醛、2,5-呋喃二甲醛、2,5-噻吩二甲醛和 2,2'-联苯二甲醛转化为相应的甲酰基羧酸，摩尔产率为 86-91%。
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