乳酸乳球菌乳酸亚种在pH反馈控制的补料分批培养中提高乳酸链球菌素产量。
Improvement of nisin production in pH feed-back controlled, fed-batch culture by Lactococcus lactis subsp. lactis.
作者信息
Lv Wenhua, Cong Wei, Cai Zhaoling
机构信息
State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, P.O. Box 353, Beijing, 100080, P.R. China.
出版信息
Biotechnol Lett. 2004 Nov;26(22):1713-6. doi: 10.1007/s10529-004-3742-6.
PMID:15604824
Abstract
Nisin production by Lactococcus lactis subsp. lactis in fed-batch culture was doubled by using a pH feed-back controlled method. Sucrose concentration was controlled at 10 g l(-1) giving 5010 IU nisin ml(-1) compared to 2660 IU nisin ml(-1) in batch culture.
摘要
通过采用pH反馈控制方法，乳酸乳球菌乳酸亚种在补料分批培养中产生的乳酸链球菌素产量增加了一倍。将蔗糖浓度控制在10 g l(-1)，可产生5010 IU/ml的乳酸链球菌素，而分批培养中为2660 IU/ml。
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