乳酸乳球菌乳酸亚种在补料分批培养中营养限制条件下的乳链菌肽生产。
Nisin production by Lactococcus lactis subsp. lactis under nutritional limitation in fed-batch culture.
作者信息
Lv Wenhua, Cong Wei, Cai Zhaoling
机构信息
State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, P.O. Box 353, Beijing 100080, PR China.
出版信息
Biotechnol Lett. 2004 Feb;26(3):235-8. doi: 10.1023/b:bile.0000013721.78288.1d.
Abstract
Nisin production was improved under nutritional limitation in fed-batch culture of Lactococcus lactis. Nisin titre reached 3887 IU ml(-1) by a slow feeding of sucrose and 4131 IU ml(-1) by slow feeding of nitrogen source, which were, respectively, 64% and 74% above the values in batch culture.
摘要
在乳酸乳球菌的补料分批培养中，营养限制条件下乳酸链球菌素的产量得到了提高。通过缓慢添加蔗糖，乳酸链球菌素效价达到3887 IU ml⁻¹，通过缓慢添加氮源，效价达到4131 IU ml⁻¹，分别比分批培养中的值高出64%和74%。
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