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儿童咽颈臂型变异型格林-巴利综合征

Pharyngeal-cervical-brachial variant Guillain-Barré syndrome in a child.

作者信息

MacLennan Suzanna C, Fahey Michael C, Lawson John A

机构信息

Department of Neurology, Sydney Children's Hospital, Australia.

出版信息

J Child Neurol. 2004 Aug;19(8):626-7. doi: 10.1177/088307380401900812.

Abstract

The pharyngeal-cervical-brachial variant of Guillain-Barré syndrome is uncommon but well recognized in the adult literature. Patients have weakness in a pharyngeal-cervical-brachial distribution with relative lower limb sparing. We describe a 12-year-old boy with predominantly pharyngeal-cervical-brachial weakness and subsequent respiratory failure. Owing to prominent bulbar symptoms, he was initially misdiagnosed as having epiglottitis. This case illustrates that the clinical spectrum of Guillain-Barré syndrome in children includes the pharyngeal-cervical-brachial variant, which is distinct from Miller-Fisher syndrome. Atypical Guillain-Barré syndrome should be considered in the differential diagnosis of a child presenting with bulbar palsy and/or respiratory failure.

摘要

吉兰-巴雷综合征的咽-颈-臂变异型并不常见,但在成人文献中已得到充分认识。患者表现为咽-颈-臂分布的肌无力,相对较少累及下肢。我们描述了一名12岁男孩,主要表现为咽-颈-臂肌无力,随后出现呼吸衰竭。由于突出的延髓症状,他最初被误诊为会厌炎。该病例表明,儿童吉兰-巴雷综合征的临床谱包括咽-颈-臂变异型,这与米勒-费雪综合征不同。对于出现延髓麻痹和/或呼吸衰竭的儿童,鉴别诊断时应考虑非典型吉兰-巴雷综合征。

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