Department of Pediatrics, İstanbul University İstanbul Faculty of Medicine, İstanbul, Turkey.
Department of Pediatrics, Şişli Etfal Training and Research Hospital, İstanbul, Turkey.
Balkan Med J. 2013 Sep;30(3):337-41. doi: 10.5152/balkanmedj.2013.8334. Epub 2013 Sep 1.
Pharyngeal-cervical-brachial (PCB) variant is a rare form of Guillan-Barre Syndrome (GBS). Antibodies against other membrane proteins like GM1b and GD1a have been found only in a small number of patients with Guillan Barre syndrome variant.
Here, we report a 5.5 year-old boy diagnosed early with positive GD1a and GD1b gangliosides of Guillan-Barre syndrome pharyngeal cervical-Brachial variant, who improved and recovered fully in a short period. This is in contrast to those whose recovery period prolongs in spite of early diagnosis and appropriate treatment and/or those who experience incomplete recovery.
In summary, diagnosis of PCB variant of GBS should be considered in infants with sudden onset bulbar symptoms and muscle weakness, and it should be kept in mind that early diagnosis and appropriate treatment can give successful outcomes.
咽颈臂（PCB）变异型是吉兰-巴雷综合征（GBS）的一种罕见形式。在少数吉兰-巴雷综合征变异型患者中，仅发现针对其他膜蛋白如 GM1b 和 GD1a 的抗体。
在这里，我们报告了一例 5.5 岁男孩，早期诊断为阳性 GD1a 和 GD1b 神经节苷脂，吉兰-巴雷综合征咽颈臂变异型，在短时间内改善并完全恢复。这与那些尽管早期诊断和适当治疗，恢复期仍延长的患者，或那些经历不完全恢复的患者形成对比。
总之，对于突然出现球部症状和肌无力的婴儿，应考虑诊断为 PCB 变异型 GBS，并且应该记住，早期诊断和适当治疗可以获得成功的结果。
