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年龄相关性黄斑变性患者视网膜下脉络膜新生血管膜手术切除的长期结果

Longterm results in surgical removal of subfoveal choroidal neovascularization in age-related macular degeneration.

作者信息

Guthoff Rainer, Schrader Wolfgang

机构信息

Department of Ophthalmology, Julius Maximilians University, Würzburg, Germany.

出版信息

Acta Ophthalmol Scand. 2004 Dec;82(6):686-90. doi: 10.1111/j.1600-0420.2004.00338.x.

Abstract

PURPOSE

This study aimed to analyse visual outcome, surgical complications and recurrence rates 3 years after removal of subretinal choroidal neovascularization (CNV) in patients with age-related macular degeneration (AMD).

METHODS

The study involved a retrospective analysis of 50 eyes of 50 patients who underwent surgical removal of CNV in AMD between February 1996 and June 1998. The minimum follow-up period was 36 months. Improvement or worsening of visual acuity (VA) was defined as a change of more than two lines.

RESULTS

The mean reduction in VA was 2.2 +/- 6.9 lines. Visual acuity improved in 12 eyes, remained stable in 16 eyes and worsened in 22 eyes. Recurrence of CNV occurred in three eyes.

CONCLUSION

After surgical excision of age-related subfoveal CNV, VA improved or stabilized in a large group of patients. Considering the development of VA and the low recurrence rate, surgical treatment seems to be beneficial compared to the natural course of CNV over a longterm follow-up of more than 3 years.

摘要

目的

本研究旨在分析年龄相关性黄斑变性(AMD)患者视网膜下脉络膜新生血管(CNV)切除术后3年的视力结果、手术并发症及复发率。

方法

本研究对1996年2月至1998年6月间50例接受AMD患者CNV手术切除的50只眼进行回顾性分析。最短随访期为36个月。视力(VA)提高或下降定义为变化超过两行。

结果

VA平均下降2.2±6.9行。12只眼视力提高,16只眼视力稳定,22只眼视力下降。3只眼发生CNV复发。

结论

年龄相关性黄斑下CNV手术切除后,一大组患者的VA改善或稳定。考虑到VA的发展及低复发率,在超过3年的长期随访中,与CNV的自然病程相比,手术治疗似乎有益。

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