Guthoff Rainer, Schrader Wolfgang
Department of Ophthalmology, Julius Maximilians University, Würzburg, Germany.
Acta Ophthalmol Scand. 2004 Dec;82(6):686-90. doi: 10.1111/j.1600-0420.2004.00338.x.
This study aimed to analyse visual outcome, surgical complications and recurrence rates 3 years after removal of subretinal choroidal neovascularization (CNV) in patients with age-related macular degeneration (AMD).
The study involved a retrospective analysis of 50 eyes of 50 patients who underwent surgical removal of CNV in AMD between February 1996 and June 1998. The minimum follow-up period was 36 months. Improvement or worsening of visual acuity (VA) was defined as a change of more than two lines.
The mean reduction in VA was 2.2 +/- 6.9 lines. Visual acuity improved in 12 eyes, remained stable in 16 eyes and worsened in 22 eyes. Recurrence of CNV occurred in three eyes.
After surgical excision of age-related subfoveal CNV, VA improved or stabilized in a large group of patients. Considering the development of VA and the low recurrence rate, surgical treatment seems to be beneficial compared to the natural course of CNV over a longterm follow-up of more than 3 years.
本研究旨在分析年龄相关性黄斑变性(AMD)患者视网膜下脉络膜新生血管(CNV)切除术后3年的视力结果、手术并发症及复发率。
本研究对1996年2月至1998年6月间50例接受AMD患者CNV手术切除的50只眼进行回顾性分析。最短随访期为36个月。视力(VA)提高或下降定义为变化超过两行。
VA平均下降2.2±6.9行。12只眼视力提高,16只眼视力稳定,22只眼视力下降。3只眼发生CNV复发。
年龄相关性黄斑下CNV手术切除后,一大组患者的VA改善或稳定。考虑到VA的发展及低复发率,在超过3年的长期随访中,与CNV的自然病程相比,手术治疗似乎有益。