Fagerholm Per, Molander Nils, Podskochy Alexander, Sundelin Staffan
Department of Ophthalmology, University Hospital, Linköping, Sweden.
Acta Ophthalmol Scand. 2004 Dec;82(6):707-13. doi: 10.1111/j.1600-0420.2004.00375.x.
To evaluate the effect of phototherapeutic keratectomy (PTK) in combination with manual scraping when removing epithelial ingrowth under a LASIK flap.
Three patients, who had undergone several surgeries following LASIK in order to remove epithelial ingrowth that was threatening vision, were treated with a flap lift, manual abrasion and PTK. The PTK was performed on both the stromal and the flap side with the aim of eliminating the threat and improving vision. Two patients underwent primary surgery to remove epithelial ingrowth with manual abrasion and PTK. The influence on vision, topography and cell recurrences was evaluated.
Uncorrected visual acuity (UCVA) and best spectacle-corrected visual acuity (BSCVA) improved in four cases and remained good in the fifth case. The refraction did not change significantly. Topography disclosed changes in the irregular astigmatism, explaining the improved BSCVA. Central epithelial ingrowth did not recur, whereas peripheral ingrowth did. The peripheral ingrowth did not progress, except in case 1, where a cyst formed that required surgery.
It is our belief that adding PTK to manual scraping improves the prognosis for eyes with epithelial ingrowth. It is mainly the central ingrowth that is positively affected. Improved adhesion between the stroma and the flap is one possible explanation.
评估准分子激光角膜切削术(PTK)联合手动刮除术在准分子原位角膜磨镶术(LASIK)瓣下上皮内生清除中的效果。
3例接受LASIK手术后因上皮内生威胁视力而进行多次手术的患者,接受了瓣掀起、手动刮除和PTK治疗。PTK在基质面和瓣面均进行,旨在消除威胁并改善视力。2例患者接受了初次手术,采用手动刮除和PTK去除上皮内生。评估对视力、地形图和细胞复发的影响。
4例患者的未矫正视力(UCVA)和最佳矫正视力(BSCVA)提高,第5例保持良好。屈光无明显变化。地形图显示不规则散光有变化,这解释了BSCVA的改善。中央上皮内生未复发,而周边内生复发。除病例1形成囊肿需要手术外,周边内生未进展。
我们认为,在手动刮除的基础上加用PTK可改善上皮内生患者的预后。主要是中央内生受到积极影响。基质与瓣之间黏附性改善是一种可能的解释。