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准分子激光角膜切削术治疗LASIK术后角膜瓣条纹的效果

Results of phototherapeutic keratectomy in the management of flap striae after LASIK.

作者信息

Steinert Roger F, Ashrafzadeh Amin, Hersh Peter S

机构信息

Centerr for Eye Research and Education, Ophthalmic Consultants of Boston, 50 Staniford Street, Suite 600, Boston, MA 02114, USA.

出版信息

Ophthalmology. 2004 Apr;111(4):740-6. doi: 10.1016/j.ophtha.2003.06.015.

Abstract

OBJECTIVE

To evaluate the efficacy of phototherapeutic keratectomy (PTK) in reducing or resolving visually significant surface irregularities resulting from flap striae after LASIK.

DESIGN

Retrospective, noncomparative case series.

PARTICIPANTS

Twenty-three eyes of 22 patients with flap striae after LASIK and reduced best-corrected visual acuity or visual symptoms that resolved with diagnostic contact lens fitting treated between January 2001 and April 2002 with at least 1 month of follow-up. The mean follow-up interval was 134 days (range, 30-354 days).

INTERVENTION

Transepithelial PTK.

MAIN OUTCOME MEASURES

Uncorrected visual acuity (UCVA), resolution or reduction of preoperative symptoms, corneal haze, and best spectacle-corrected visual acuity (BSCVA).

RESULTS

Mean BSCVA and UCVA improved significantly from 20/32 and 20/48 to 20/22 and 20/33 (P<0.0001 and P = 0.027), respectively, after PTK. There was a significant mean hyperopic shift of 0.88 diopters (D; P = 0.002, range, -1.38 to +3.88 D). Fourteen eyes (61%) were clinically clear, 6 eyes (23%) had trace haze, and 3 eyes (16%) had 1+ haze at the last follow-up visit. Mean spherical equivalent refractive error before LASIK was -7.23 D (range, -2.88 to -13.55 D). Twenty-two of 23 eyes had significant qualitative resolution or reduction of preoperative visual symptoms.

CONCLUSIONS

In cases of visually significant LASIK flap striae, PTK is effective in improving best-corrected visual acuity and reducing visual symptoms. High myopia may be a risk factor for development of visually significant microstriae. Development of anterior stromal haze did not exceed 1+ density and was not correlated to either the number of laser pulses or the length of the follow-up period.

摘要

目的

评估光治疗性角膜切削术(PTK)在减轻或消除准分子激光原位角膜磨镶术(LASIK)后因瓣状条纹导致的明显角膜表面不规则方面的疗效。

设计

回顾性、非对照病例系列。

研究对象

2001年1月至2002年4月期间接受治疗的22例LASIK术后出现瓣状条纹且最佳矫正视力下降或有视觉症状(经诊断性配戴隐形眼镜后症状缓解)的患者的23只眼,随访至少1个月。平均随访间隔为134天(范围30 - 354天)。

干预措施

经上皮PTK。

主要观察指标

裸眼视力(UCVA)、术前症状的缓解或减轻、角膜 haze、最佳眼镜矫正视力(BSCVA)。

结果

PTK术后,平均BSCVA和UCVA分别从20/32和20/48显著提高到20/22和20/33(P < 0.0001和P = 0.027)。平均有0.88屈光度(D;P = 0.002,范围 - 1.38至 + 3.88 D)的明显远视性移位。在最后一次随访时,14只眼(61%)临床清晰,6只眼(23%)有微量 haze,3只眼(16%)有1 + haze。LASIK术前平均等效球镜屈光不正为 - 7.23 D(范围 - 2.88至 - 13.55 D)。23只眼中的22只眼术前视觉症状有显著的定性缓解或减轻。

结论

在LASIK瓣状条纹导致明显视力下降的病例中,PTK在提高最佳矫正视力和减轻视觉症状方面有效。高度近视可能是导致明显微条纹形成的危险因素。前部基质 haze 的形成不超过1 + 密度,且与激光脉冲次数或随访时间长短均无相关性。

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