Steinert Roger F, Ashrafzadeh Amin, Hersh Peter S
Centerr for Eye Research and Education, Ophthalmic Consultants of Boston, 50 Staniford Street, Suite 600, Boston, MA 02114, USA.
Ophthalmology. 2004 Apr;111(4):740-6. doi: 10.1016/j.ophtha.2003.06.015.
To evaluate the efficacy of phototherapeutic keratectomy (PTK) in reducing or resolving visually significant surface irregularities resulting from flap striae after LASIK.
Retrospective, noncomparative case series.
Twenty-three eyes of 22 patients with flap striae after LASIK and reduced best-corrected visual acuity or visual symptoms that resolved with diagnostic contact lens fitting treated between January 2001 and April 2002 with at least 1 month of follow-up. The mean follow-up interval was 134 days (range, 30-354 days).
Transepithelial PTK.
Uncorrected visual acuity (UCVA), resolution or reduction of preoperative symptoms, corneal haze, and best spectacle-corrected visual acuity (BSCVA).
Mean BSCVA and UCVA improved significantly from 20/32 and 20/48 to 20/22 and 20/33 (P<0.0001 and P = 0.027), respectively, after PTK. There was a significant mean hyperopic shift of 0.88 diopters (D; P = 0.002, range, -1.38 to +3.88 D). Fourteen eyes (61%) were clinically clear, 6 eyes (23%) had trace haze, and 3 eyes (16%) had 1+ haze at the last follow-up visit. Mean spherical equivalent refractive error before LASIK was -7.23 D (range, -2.88 to -13.55 D). Twenty-two of 23 eyes had significant qualitative resolution or reduction of preoperative visual symptoms.
In cases of visually significant LASIK flap striae, PTK is effective in improving best-corrected visual acuity and reducing visual symptoms. High myopia may be a risk factor for development of visually significant microstriae. Development of anterior stromal haze did not exceed 1+ density and was not correlated to either the number of laser pulses or the length of the follow-up period.
评估光治疗性角膜切削术(PTK)在减轻或消除准分子激光原位角膜磨镶术(LASIK)后因瓣状条纹导致的明显角膜表面不规则方面的疗效。
回顾性、非对照病例系列。
2001年1月至2002年4月期间接受治疗的22例LASIK术后出现瓣状条纹且最佳矫正视力下降或有视觉症状(经诊断性配戴隐形眼镜后症状缓解)的患者的23只眼,随访至少1个月。平均随访间隔为134天(范围30 - 354天)。
经上皮PTK。
裸眼视力(UCVA)、术前症状的缓解或减轻、角膜 haze、最佳眼镜矫正视力(BSCVA)。
PTK术后,平均BSCVA和UCVA分别从20/32和20/48显著提高到20/22和20/33(P < 0.0001和P = 0.027)。平均有0.88屈光度(D;P = 0.002,范围 - 1.38至 + 3.88 D)的明显远视性移位。在最后一次随访时,14只眼(61%)临床清晰,6只眼(23%)有微量 haze,3只眼(16%)有1 + haze。LASIK术前平均等效球镜屈光不正为 - 7.23 D(范围 - 2.88至 - 13.55 D)。23只眼中的22只眼术前视觉症状有显著的定性缓解或减轻。
在LASIK瓣状条纹导致明显视力下降的病例中,PTK在提高最佳矫正视力和减轻视觉症状方面有效。高度近视可能是导致明显微条纹形成的危险因素。前部基质 haze 的形成不超过1 + 密度,且与激光脉冲次数或随访时间长短均无相关性。