Iwasaki Akinori, Walczak Tadeusz, Grinberg Oleg, Swartz Harold M
Department of Radiology, Dartmouth Medical School, 702 Vail, Hanover, NH 03755, USA.
Appl Radiat Isot. 2005 Feb;62(2):133-9. doi: 10.1016/j.apradiso.2004.08.038.
We have determined the properties of the various signals that are observed in vivo so this information can be used to develop procedures for data acquisition and data analysis that will enable the accurate determination of radiation-induced dose with a resolution of 50cGy. Using the 1200MHz in vivo EPR spectrometer and isolated human teeth, we found four types of signals whose properties overlap, but also have some distinct properties that can be exploited to resolve them. The intrinsic background signal in human teeth differs modestly from the radiation-induced signal in g-factor, shape, and power saturation. Random noise from instrumental conditions can be reduced with signal averaging. The microphonic signal varies with the particular experimental setup and has some properties similar to real EPR signals, but is constant if the conditions are not changed. It can be suppressed by improvements in hardware and software, or subtracted.
我们已经确定了体内观察到的各种信号的特性,因此这些信息可用于开发数据采集和数据分析程序,从而能够以50cGy的分辨率准确测定辐射诱导剂量。使用1200MHz体内电子顺磁共振光谱仪和离体人牙,我们发现了四种类型的信号,它们的特性相互重叠,但也有一些可用于分辨它们的独特特性。人牙中的固有背景信号在g因子、形状和功率饱和方面与辐射诱导信号略有不同。仪器条件产生的随机噪声可通过信号平均来降低。颤噪信号随特定实验设置而变化,具有一些与真实电子顺磁共振信号相似的特性,但如果条件不变则是恒定的。可以通过硬件和软件的改进来抑制它,或者将其减去。