转录因子、胰腺发育与β细胞维持
Transcription factors, pancreatic development, and beta-cell maintenance.
作者信息
Cerf M E, Muller C J F, Du Toit D F, Louw J, Wolfe-Coote S A
机构信息
Diabetes Research Group, Medical Research Council, Tygerberg, South Africa.
出版信息
Biochem Biophys Res Commun. 2005 Jan 28;326(4):699-702. doi: 10.1016/j.bbrc.2004.10.217.
PMID:15607725
Abstract
Transcription factors play an important role during pancreatic development ensuring normal differentiation of the islet endocrine cells. In mature beta-cells, expression of specific transcription factors is essential in maintaining normal beta-cell function.
摘要
转录因子在胰腺发育过程中发挥着重要作用，确保胰岛内分泌细胞的正常分化。在成熟的β细胞中，特定转录因子的表达对于维持正常的β细胞功能至关重要。
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