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基因探索者:一款用于微阵列数据可视化与分析的交互式网络应用程序。

GeneXplorer: an interactive web application for microarray data visualization and analysis.

作者信息

Rees Christian A, Demeter Janos, Matese John C, Botstein David, Sherlock Gavin

机构信息

Dept. of Genetics, 300 Pasteur Drive, Stanford University Medical School, Stanford, CA 94305-5120, USA.

出版信息

BMC Bioinformatics. 2004 Oct 1;5:141. doi: 10.1186/1471-2105-5-141.

Abstract

BACKGROUND

When publishing large-scale microarray datasets, it is of great value to create supplemental websites where either the full data, or selected subsets corresponding to figures within the paper, can be browsed. We set out to create a CGI application containing many of the features of some of the existing standalone software for the visualization of clustered microarray data.

RESULTS

We present GeneXplorer, a web application for interactive microarray data visualization and analysis in a web environment. GeneXplorer allows users to browse a microarray dataset in an intuitive fashion. It provides simple access to microarray data over the Internet and uses only HTML and JavaScript to display graphic and annotation information. It provides radar and zoom views of the data, allows display of the nearest neighbors to a gene expression vector based on their Pearson correlations and provides the ability to search gene annotation fields.

CONCLUSIONS

The software is released under the permissive MIT Open Source license, and the complete documentation and the entire source code are freely available for download from CPAN http://search.cpan.org/dist/Microarray-GeneXplorer/.

摘要

背景

在发布大规模微阵列数据集时,创建补充网站非常有价值,在该网站上可以浏览完整数据或与论文中的图表相对应的选定子集。我们着手创建一个CGI应用程序,该应用程序包含一些现有独立软件的许多功能,用于可视化聚类微阵列数据。

结果

我们展示了GeneXplorer,这是一个用于在网络环境中进行交互式微阵列数据可视化和分析的网络应用程序。GeneXplorer允许用户以直观的方式浏览微阵列数据集。它通过互联网提供对微阵列数据的简单访问,并且仅使用HTML和JavaScript来显示图形和注释信息。它提供数据的雷达图和缩放视图,允许基于皮尔逊相关性显示与基因表达向量最近的邻居,并提供搜索基因注释字段的功能。

结论

该软件根据宽松的麻省理工学院开源许可发布,完整的文档和整个源代码可从CPAN http://search.cpan.org/dist/Microarray-GeneXplorer/免费下载。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17d1/523853/f6f3069cfd40/1471-2105-5-141-1.jpg

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