Sheth Bhavisha P, Thaker Vrinda S
Department of Biosciences, Centre for Advanced Studies in Plant Biotechnology and Genetic Engineering, Saurashtra University, Rajkot, 360005, Gujarat, India,
Planta. 2014 Jul;240(1):33-54. doi: 10.1007/s00425-014-2059-5. Epub 2014 Mar 27.
Plants dwelling at the base of biological food chain are of fundamental significance in providing solutions to some of the most daunting ecological and environmental problems faced by our planet. The reductionist views of molecular biology provide only a partial understanding to the phenotypic knowledge of plants. Systems biology offers a comprehensive view of plant systems, by employing a holistic approach integrating the molecular data at various hierarchical levels. In this review, we discuss the basics of systems biology including the various 'omics' approaches and their integration, the modeling aspects and the tools needed for the plant systems research. A particular emphasis is given to the recent analytical advances, updated published examples of plant systems biology studies and the future trends.
处于生物食物链底层的植物对于解决我们星球面临的一些最严峻的生态和环境问题具有至关重要的意义。分子生物学的还原论观点仅能部分理解植物的表型知识。系统生物学通过采用整体方法整合各个层次水平的分子数据，提供了对植物系统的全面看法。在本综述中，我们讨论了系统生物学的基础知识，包括各种“组学”方法及其整合、建模方面以及植物系统研究所需的工具。特别强调了最近的分析进展、植物系统生物学研究的最新已发表实例以及未来趋势。
