Manegold C, Patzschke U
Dtsch Med Wochenschr. 1979 Jun 8;104(23):846-8. doi: 10.1055/s-0028-1104000.
Typical signs of left ventricular hypertrophy (LVH) were present in the ECG of 36 (10 women, 26 men) of 127 persons with essential hypertension (46 women, 81 men). After a two-year course of combined drug treatment (chlortalidone, reserpine, methyl-dopa, hydralazine) with effective blood-pressure reduction LVH was still present in the ECG of 29, after a four-year course of only 15 among 36, i. e. a reduction in the presence of LVH of nearly 60%. Since the patients' body-weight remained unchanged during this period, the regression in ECG changes is ascribed to the effectiveness of the drug treatment.
127例原发性高血压患者（46名女性，81名男性）中，有36人（10名女性，26名男性）的心电图显示有典型的左心室肥厚（LVH）迹象。在进行为期两年的联合药物治疗（氯噻酮、利血平、甲基多巴、肼屈嗪）且有效降低血压后，29人的心电图中仍存在LVH；在进行为期四年的治疗后，36人中只有15人存在LVH，即LVH的发生率降低了近60%。由于在此期间患者体重保持不变，心电图变化的消退归因于药物治疗的有效性。
