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用于治疗阻塞性睡眠呼吸暂停的抬高体位

Elevated posture for the management of obstructive sleep apnea.

作者信息

Skinner Margot A, Kingshott Ruth N, Jones David R, Homan Sean D R, Taylor D Robin

机构信息

Respiratory Research Unit, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.

出版信息

Sleep Breath. 2004 Dec;8(4):193-200. doi: 10.1007/s11325-004-0193-1.

DOI:10.1007/s11325-004-0193-1
PMID:15611894
Abstract

This study aimed to evaluate the effectiveness of elevated posture in the management of obstructive sleep apnea (OSA). Fourteen subjects presenting with mild-moderate OSA, (apnea-hypopnea index [AHI] 10 to 60/h), were included in a randomized crossover investigation. A shoulder-head elevation pillow (SHEP) was compared with nasal continuous positive airway pressure (nCPAP) therapy. Treatment success was defined as AHI<or=10/h and partial success as AHI>10<16/h. Four subjects achieved treatment success with the SHEP and three achieved partial success. The remaining seven subjects were treatment failures. In contrast, success was achieved with nCPAP in 12 subjects. One subject achieved partial success and one was a treatment failure. With the SHEP, the mean AHI decreased from 27+/-12/h to 21+/-17/h. With nCPAP, the mean AHI was 5+/-3/h; (p=0.008 for the difference between treatments). Although somewhat variable, these data provide evidence that elevated posture during sleep is helpful in the management of OSA in some individuals. Results support the use of elevated posture as second-line therapy in the management of OSA. However, no relationships could be identified between baseline data, including the identification of positional OSA, and objective outcomes that might predict patients who are likely to benefit from treatment in an elevated position.

摘要

本研究旨在评估抬高姿势在阻塞性睡眠呼吸暂停(OSA)管理中的有效性。14名患有轻度至中度OSA(呼吸暂停低通气指数[AHI]为10至60次/小时)的受试者被纳入一项随机交叉研究。将肩枕抬高枕头(SHEP)与经鼻持续气道正压通气(nCPAP)治疗进行比较。治疗成功定义为AHI≤10次/小时,部分成功定义为AHI>10且<16次/小时。4名受试者使用SHEP取得治疗成功,3名受试者取得部分成功。其余7名受试者治疗失败。相比之下,12名受试者使用nCPAP取得成功。1名受试者取得部分成功,1名受试者治疗失败。使用SHEP时,平均AHI从27±12次/小时降至21±17次/小时。使用nCPAP时,平均AHI为5±3次/小时;(治疗之间的差异p = 0.008)。尽管存在一定差异,但这些数据提供了证据,表明睡眠期间抬高姿势对某些个体的OSA管理有帮助。结果支持将抬高姿势用作OSA管理的二线治疗方法。然而,在包括体位性OSA识别在内的基线数据与可能预测哪些患者可能从抬高体位治疗中受益的客观结果之间,未发现相关性。

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