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“网球技术”与经鼻持续气道正压通气治疗体位性阻塞性睡眠呼吸暂停低通气综合征的疗效比较

Efficacy of the 'tennis ball technique' versus nCPAP in the management of position-dependent obstructive sleep apnoea syndrome.

作者信息

Skinner Margot A, Kingshott Ruth N, Filsell Sue, Taylor D Robin

机构信息

Respiratory Research Unit, Dunedin School of Medicine, School of Physiotherapy, University of Otago, Dunedin, New Zealand.

出版信息

Respirology. 2008 Sep;13(5):708-15. doi: 10.1111/j.1440-1843.2008.01328.x.

DOI:10.1111/j.1440-1843.2008.01328.x
PMID:18713092
Abstract

BACKGROUND AND OBJECTIVE

Avoidance of sleep in the supine position is recommended in the management of position-dependent OSA hypopnoea syndrome (OSAHS). Our aim was to evaluate the efficacy of a thoracic anti-supine band (TASB), designed to mimic the so-called 'tennis ball technique', compared with nasal CPAP (nCPAP).

METHODS

Twenty adults with mild to moderately severe position-dependent OSAHS (mean AHI +/- SD) 22.7 +/- 12.0/H (range 6.0-51.2); AHI supine, 59.6 +/- 27.5/H, were included in a randomized cross-over trial. Portable sleep studies were undertaken at baseline and after 1 month on each treatment. A successful treatment outcome was defined as AHI <or= 10/H.

RESULTS

Mean AHI was 12.0 +/- 14.5/H with the TASB and 4.9 +/- 3.9/H with nCPAP (P = 0.02; 95% confidence interval for the difference: -13.1 to -1.0). With the TASB, treatment 'success' was achieved in 13/18 subjects, whereas 'success' was achieved in 16/18 subjects using nCPAP (P = 0.004). In the two subjects with baseline AHI < 10/H, AHI remained below 10 for both therapies. The TASB successfully reduced time spent in the supine position. Mean percentage supine sleep time was 6.3 +/- 5.9% with the TASB, and 35.4 +/- 34.1% with nCPAP (P < 0.001). No significant differences in sleep efficiency or subjective responses were observed between treatments.

CONCLUSIONS

Control of body position during sleep using an anti-supine device mimicking the so-called 'tennis ball technique' provides benefit in the management of position-dependent OSAHS in subjects who meet strict inclusion criteria. The overall improvement is, however, less than for nCPAP.

摘要

背景与目的

在体位性阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的管理中,建议避免仰卧位睡眠。我们的目的是评估一种模仿所谓“网球技术”设计的胸部防仰卧带(TASB)与鼻持续气道正压通气(nCPAP)相比的疗效。

方法

20名轻度至中度重度体位性OSAHS的成年人(平均呼吸暂停低通气指数[AHI]±标准差)22.7±12.0次/小时(范围6.0 - 51.2);仰卧位AHI为59.6±27.5次/小时,被纳入一项随机交叉试验。在基线时以及每种治疗1个月后进行便携式睡眠研究。成功的治疗结果定义为AHI≤10次/小时。

结果

使用TASB时平均AHI为12.0±14.5次/小时,使用nCPAP时为4.9±3.9次/小时(P = 0.02;差异的95%置信区间:-13.1至-1.0)。使用TASB时,13/18名受试者治疗“成功”,而使用nCPAP时16/18名受试者“成功”(P = 0.004)。在两名基线AHI < 10次/小时的受试者中,两种治疗的AHI均保持在10以下。TASB成功减少了仰卧位的时间。使用TASB时仰卧位睡眠时间的平均百分比为6.3±5.9%,使用nCPAP时为35.4±34.1%(P < 0.001)。治疗之间在睡眠效率或主观反应方面未观察到显著差异。

结论

使用模仿所谓“网球技术”的防仰卧装置控制睡眠期间的身体姿势,对于符合严格纳入标准的体位性OSAHS患者的管理有益。然而,总体改善程度小于nCPAP。

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