Maruti Sonia S, Feskanich Diane, Colditz Graham A, Frazier A Lindsay, Sampson Laura A, Michels Karin B, Hunter David J, Spiegelman Donna, Willett Walter C
Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston 02215, MA, USA.
Am J Epidemiol. 2005 Jan 1;161(1):89-97. doi: 10.1093/aje/kwi019.
Many cancers have long latency periods, and dietary factors in adolescence may plausibly affect cancer occurrence in adulthood. Because of a lack of prospective data, retrospective collection of data on adolescent diet is essential. The authors evaluated a 124-item high school food frequency questionnaire (HS-FFQ) assessing diet during high school (15-35 years in the past) that was completed in 1998 by 45,947 US women in the Nurses' Health Study II (NHSII) cohort. To assess reproducibility, the authors readministered the HS-FFQ approximately 4 years later to 333 of these women. The mean Pearson correlation for 38 nutrient intakes was 0.65 (range, 0.50-0.77), and the mean Spearman rank correlation for food intakes was 0.60 (range, 0.37-0.77). Current adult diet was only weakly correlated with recalled adolescent diet (for nutrient intakes, mean r = 0.20). For assessment of validity, 272 mothers of the NHSII participants were asked to report information on their daughters' adolescent diets using the HS-FFQ. In this comparison, the mean Pearson correlation was 0.40 (range, 0.13-0.59) for nutrients, and the mean Spearman rank correlation for foods was 0.30 (range, 0.10-0.61). While further studies are warranted, these findings imply that this food frequency questionnaire provides a reasonable record of adolescent diet.
许多癌症都有较长的潜伏期，青春期的饮食因素可能会对成年期癌症的发生产生影响。由于缺乏前瞻性数据，回顾性收集青少年饮食数据至关重要。作者评估了一份包含124个条目的高中食物频率问卷（HS-FFQ），该问卷用于评估高中时期（过去15 - 35年）的饮食情况，1998年美国护士健康研究II（NHSII）队列中的45947名女性完成了这份问卷。为评估可重复性，作者在大约4年后对其中333名女性重新进行了HS-FFQ调查。38种营养素摄入量的平均皮尔逊相关系数为0.65（范围为0.50 - 0.77），食物摄入量的平均斯皮尔曼等级相关系数为0.60（范围为0.37 - 0.77）。当前成人饮食与回忆起的青少年饮食之间的相关性较弱（营养素摄入量的平均r值 = 0.20）。为评估有效性，作者让NHSII参与者的272位母亲使用HS-FFQ报告其女儿青少年时期的饮食信息。在这次比较中，营养素的平均皮尔逊相关系数为0.40（范围为0.13 - 0.59），食物的平均斯皮尔曼等级相关系数为0.30（范围为0.10 - 0.61）。虽然还需要进一步研究，但这些发现表明这份食物频率问卷为青少年饮食提供了合理的记录。
