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不同抗原-抗体系统引起的过敏反应之间的干扰研究。

Studies on the interference between the allergic reactions caused by different antigen-antibody systems.

作者信息

Sindo T, Haga K, Yamamoto Y, Hayashi Y, Ozawa K

出版信息

Int Arch Allergy Appl Immunol. 1979;59(4):447-51. doi: 10.1159/000232294.

Abstract

Interference between two different in vivo antigen-antibody reactions which occurred simultaneously was studied in guinea pigs. Animals were presensitized with an aqueous fraction (CP) extracted from cells of Corynebacterium equi, strain KO-85. Skin reactions of the Arthus type elicited by the CP fraction inhibited passive cutaneous anaphylaxis (PCA) induced by bovine serum albumin (BSA) and rabbit anti-BSA serum. PCA reactions of the CP-sensitized animals were also inhibited upon simultaneous challenges of BSA and the CP as evidence by reduction of PCA titer of the anti-BSA serum.

摘要

在豚鼠中研究了同时发生的两种不同体内抗原 - 抗体反应之间的干扰。用从马棒状杆菌KO - 85菌株细胞中提取的水性组分(CP)对动物进行预先致敏。CP组分引发的阿瑟斯型皮肤反应抑制了由牛血清白蛋白(BSA)和兔抗BSA血清诱导的被动皮肤过敏反应(PCA)。当同时用BSA和CP进行攻击时,CP致敏动物的PCA反应也受到抑制,这通过抗BSA血清的PCA滴度降低得到证明。

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