Zaune U, Spies C, Pauli M H, Boeden G, Martin E
Klinik für Anaesthesiologie und operative Intensivmedizin, Klinikum Nürnberg.
Anaesthesist. 1992 Feb;41(2):71-5.
Several systems for mixed-venous oximetry are now available. There are one three-wave-length system (Abbott) and three two-wave-length systems with (Spectramed) and without automatic correction for hemoglobin or hematocrit (Edwards). The purpose of this prospective randomized study was to compare the different systems and to examine the accuracy of continuous mixed-venous oximetry during abdominal aortic surgery. Eighty patients had a radial artery cannula and one of the following fiberoptic pulmonary artery catheters inserted before induction of anesthesia: Swan-Ganz oximetry TD catheter (Edwards), Swan-Ganz flow-directed oximetry thermodilution paceport catheter (Baxter, Edwards Division), SpectraCath STP (Spectramed), and Opticath (Abbott). Mixed-venous O2 saturation was monitored by oximetry computers: SAT-1 (Edwards), SAT-2 (Baxter, Edwards Division), Hemopro2 (Spectramed), and Oximetrix 3 (Abbott). As a method of reference, mixed-venous blood samples were drawn and immediately analyzed by an OSM3-Hemoximeter. Data sets were obtained at eight predetermined times. Hemoglobin was kept constant at +/- 1 g.dl-1. Continuous oximetry in comparison to in-vitro measurements yielded a correlation coefficient of r = 0.873 (P less than 0.0001) and a value of bias and precision (b +/- p) of -0.9 +/- 2.6% for the SAT-1, r = 0.815 (P less than or equal to 0.0001) and b +/- p = -2.2 +/- 2.5% for the SAT-2, r = 0.901 (P less than or equal to 0.0001) and b +/- p = 0.35 +/- 2.5% for the Hemopro2, and r = 0.920 (P less than or equal to 0.0001) and b +/- p = 0.1 +/- 1.8% for the Oximetrix 3, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
目前有几种用于混合静脉血氧饱和度测定的系统。有一个三波长系统(雅培公司)和三个两波长系统,其中一个带有(思创美公司)自动校正血红蛋白或血细胞比容功能,另一个(爱德华兹公司)则没有。这项前瞻性随机研究的目的是比较不同系统,并检验腹主动脉手术期间连续混合静脉血氧饱和度测定的准确性。80例患者在麻醉诱导前插入桡动脉导管,并插入以下一种光纤肺动脉导管:Swan-Ganz血氧饱和度测定TD导管(爱德华兹公司)、Swan-Ganz血流导向型血氧饱和度测定热稀释起搏端口导管(百特公司,爱德华兹分部)、SpectraCath STP(思创美公司)和Opticath(雅培公司)。混合静脉血氧饱和度由血氧饱和度测定计算机监测:SAT-1(爱德华兹公司)、SAT-2(百特公司,爱德华兹分部)、Hemopro2(思创美公司)和Oximetrix 3(雅培公司)。作为参考方法,采集混合静脉血样并立即用OSM3-血氧计进行分析。在八个预定时间获取数据集。血红蛋白保持在±1 g.dl-1不变。与体外测量相比,连续血氧饱和度测定得出,SAT-1的相关系数r = 0.873(P < 0.0001),偏差和精密度值(b±p)为-0.9±2.6%;SAT-2的r = 0.815(P≤0.0001),b±p = -2.2±2.5%;Hemopro2的r = 0.901(P≤0.0001),b±p = 0.35±2.5%;Oximetrix 3的r = 0.920(P≤0.0001),b±p = 0.1±1.8%。(摘要截断于250字)